Naked Mole-rat San Diego Zoo Animals & Plants

hair mole rat

Today, Joe is still a wrinkly rodent with a taste for root veggies. But he’s now Buffenstein’s oldest naked mole rat, the oldest ever recorded—Joe turns 39 this year. That’s nine times older than typical mice live, and five times more than other similarly sized rodents. Naked mole rats don't look like they'd be one of nature's superstars.

Naked mole-rats eat their poop!

They mole rats rarely leave their burrows, though they may sometimes go above ground to gather nesting materials and dig up seeds. Scientists are now further studying the naked mole-rat to see whether we might be able to make the human pain system similarly impervious to acid pain. This could be extremely useful for cancer and arthritis sufferers, for whom build-ups of acid in body tissue can be a major contributor to chronic pain. As the name might suggest, naked mole-rats buck the mammalian trend by almost completely lacking hair or fur.

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Clinical trials are underway to test it against human aging. Perhaps NRF2 helps mole rats escape the onset of multiple aging-related diseases simultaneously. The way naked mole-rats mate and socially organise is more akin to certain insect species than to mammals. Like some species of bees and ants, naked mole-rats are eusocial, living in 100-strong groups headed by a sole breeding female, the queen. But while insects command their colonies with pheromones, the naked mole-rat queen uses physical aggression to keep their groups digging tunnels, foraging, and defending entrances. But the naked mole-rat and the Damaraland mole-rat are the only two mammal species that are eusocial (yew-SO-shul).

They’re impervious to some types of pain

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In a zero oxygen environment, the Naked Mole-Rat can live for up to 18-minutes without suffering any harm. The eyes of the naked mole-rat are very small, and this contributes to their poor vision – but they are not blind as is often assumed, and can burrow with eyes closed. It is almost completely cold blooded, has no pain sensitivity in its skin, has a very low metabolism, as well as low respiration. The peculiarities of naked mole-rat behaviour are captivating in themselves.

As the tunnels of the naked mole-rat habitat will have low oxygen levels, the creature has adapted to this and can live quite comfortably in the harsh conditions. They have underdeveloped lungs and the blood of the naked mole-rat has a high affinity for oxygen which results in a more efficient uptake of it. Naked mole-rats are also highly resilient to low oxygen conditions.

For instance, the mole-rats’ blood vessels retain their elasticity, and the queens do not enter menopause and are still able to breed even at the age of thirty. Naked mole-rats feast on tubers and roots, which requires strong chompers. According to the San Diego Zoo, those two prominent front teeth continue to grow but are kept at a reasonable length thanks to constant filing.

Reproduction and development

A naked mole-rat colony works together for the good of the group, and that includes sharing food. Scientists who study naked mole-rat behavior have even seen pups take turns nursing. If a food scout finds a tasty root or tuber, he or she carves off a piece with those sharp teeth and dashes back to the group while chirping and waving the morsel overhead! The other workers follow the scout's scent back to the new food source and bring it back, piece by piece, to the food chamber. She fell in love with naked mole rats on first sight at the Pacific Science Center in Seattle.

But the queen is good to her pups, and tends them diligently — with the help of the rest of the colony. Queens typically produce a litter of about 11 to 12 pups, although litters with as many as 27 pups have been noted. The queen will nurse her pups for about a month, and then the pups join their colony mates on the mole-rats’ regular diet of underground plant parts, like roots and succulent tubers. Naked mole-rats get all of their water from their food (and the queen, dutifully tended to by her subjects, gets all of her food served to her). These are some of the most amazing facts about naked mole-rats. Many might laugh out loud at their comical appearance, but if there’s anything that we’ve learned today is that these rodents have incredible powers that might one day save many human lives.

hair mole rat

As far as we can tell, he’ll just want a few nibbles of sweet potato, some quality time with his queen, and maybe a little wrinkle cream. (“We are fairly similar to rodents,” Gorbunova says. “It's not like they're some kind of sea sponge.”) But while a Tesla is a car, its spare parts won’t fix your cousin’s Ford Pinto. Maybe the really good stuff is built differently—and is irreconcilably untranslatable. Their diet consists mainly of roots, bulbs, tubers, and aloe leaves. Invertebrates, such as earthworms, larvae and white ants, are occasionally eaten.

About 25 percent of a naked mole-rat's muscle mass is in its jaws. Naked mole-rats use their powerful jaws and very large incisors to dig through hard-packed soil. Their diet is high in cellulose, which is difficult to digest. Naked mole-rats have high densities of gut fauna that aid in digestion. They also regularly practice coprophagy, the reingestion of feces, which allows them to maximize their uptake of nutrients from their food. Researchers at the University of Texas Southwestern Medical Center previously grew mice with partial rats’ brains.

Your DNA accrues damage from oxidizing molecules, which also attack proteins and fats, tearing you apart microscopically from the inside. Communication between cells breaks down, and inflammation cranks up. There’s no single force that drives cellular aging; it’s a network of feedback loops.

Some evidence suggests that a key difference in one of the meshwork of substances providing structural and nutritional support to cells prevents them from reproducing uncontrollably. However, others have observed different results, so further investigation is needed. Naked mole-rat tunnel systems can have a cumulative length of two to three miles.

Some humans can go into shock when they ingest capsaicin (the substance that makes chili peppers hot) but naked mole-rats don’t feel any pain when coming in contact with the substance. What’s more, when they encounter an acid, molecules in the creature’s pain-sensing nerves turn the acid into an anesthetic. So, rather than hurting them, a strong acid actually numbs the naked mole-rats.

Transgenic mice overexpressing nmrHas2 are resistant to both spontaneous and induced cancer. This wide coverage allows them to have enough room for all the colony, as well as enough roots to snack upon. They live virtually all their life in complete darkness underground. This is why they are called ‘naked’ and their skin is a wrinkled pink or yellowish color. As yet, we’re not exactly sure what gives them their resistance.

These rodents are native to the grasslands of East Africa, and are mostly hairless, wrinkled, and blind. And yet, they've evolved some special behaviors and features that help them thrive in harsh environments in which other mammals (humans included) would wither. They are often seen as pests, especially for sweet potato farmers because they can destroy much of a crop yield by eating the roots of plants. Due to habitat fragmentation, naked mole rats may face the threat of an unhealthy genetic population in the future. The Rochester team hopes the naked mole rat findings will lead to drugs that can affect such protein production.

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